Late-Breaking Abstracts Presented throughout ATS 2011

The 2011 program will once again include late-breaking scientific abstracts on research that was not completed or submitted by the initial November 2010 deadline. The Society accepted abstracts on important basic, translational and clinical discoveries until early February 2011. Below is a selection of some of the most interesting late-breakers that will be presented at ATS 2011. See the final program for the times and locations of these and other sessions.

Sunday, May 15
A20 “Emerging Approaches to Respiratory Infections: Late-Breaking Abstracts”
Abstract 22562
Prospective Multicenter Study of Bacterial Ventilator-Associated Pneumonia Complicating Severe ARDS
L. Papazian, Marseille, France

Abstract 22605
Rifapentine Exposure in a Trial of Daily Rifapentine Compared to Rifampin During The Intensive Phase of TB Treatment
M. Weiner, San Antonio, TX

Abstract 22610
Mice Haploinsufficient for the Histone Methyltransferase Mll Exhibit Decreased Inflammatory Responses During Polymicrobial Sepsis
W. F. Carson, Ann Arbor, MI

Abstract 22717
Cartridge-Based Automated Nucleic Acid Amplification Test (Xpert MTB/RIF) for the Diagnosis of Pulmonary Tuberculosis In HIV-Infected and Uninfected Children: A Prospective Study
H. J. Zar, Cape Town, South Africa

A29 “Stem Cells: Who Are You, How Can You Help Me and What Do You Need?”
Abstract 22679
Lineage Tracing of Mature Type 2 Alveolar Epithelial Cells Reveals New Insights Into Alveolar Maintenance and Repair
C. E. Barkauskas, Durham, N.C.

Abstract 22726
Directed Differentiation of Mouse Embryonic Stem Cells Into Primordial Lung Progenitor Cells
F. J. Hawkins, Boston, MA

Monday, May 16
B19 “Emerging Insights Into Asthma Genomics, Biomarkers and Therapeutics: Late-Breaking Abstracts”
Abstract 22651
Genome Wide Transcriptome Analysis Suggests Novel Mechanisms in Severe Childhood Asthma
C. Orsmark Pietras, Huddinge, Sweden

Abstract 22818
Identification Of Novel Genes That Contribute To Both Asthma And COPD, With Replication in a Large Population-Based Cohort
J. Smolonska, Groningen, Netherlands

Abstract 22916
5-Year Safety of Bronchial Thermoplasty Demonstrated in Patients With Severe Refractory Asthma: Research in Severe Asthma (RISA) Trial
I. D. Pavord, Leicester, United Kingdom

Tuesday, May 17
C109 “Omics Approaches to Lung Diseases”
Abstract 22782
Estradiol-Induced Alterations of the Extracellular Matrix and Activation of Matrix Metalloproteinase 2 Are Associated With the Lung Metastasis of Tuberin-Null Cells in a Xenograft Model of Lymphangioleiomyomatosis (LAM)
J. J. Yu, Boston, MA

Wednesday, May 18 
D30 “Novel Insights Into Chronic Lung Disease and Pulmonary Hypertension: Late-Breaking Abstracts”
Abstract 22557
Cigarette Smoke Induces the Release of DAMPS by Necrotic Epithelial Cells, Causing an Innate Immune Response
G. J. Zijlstra, Groningen, Netherlands

Abstract 22568
Risks Factors and Mortality Associated With Doppler-Defined-Pulmonary Hypertension in Thalassemia Major: A Report from the Thalassemia Clinical Research Network Longitudinal Cohort Study
C. R. Morris, Oakland, CA

Abstract 22609
ADAM 15 Protects the Lung From Cigarette Smoke-Induced Lung Inflammation and Pulmonary Emphysema In Mice
T. Nakajima, Boston, MA

Abstract 22727
Oral S-Nitrosoglutathione Reductase Inhibitors Attenuate Pulmonary Inflammation And Decrease Airspace Enlargement in Experimental Models of Chronic Obstructive Pulmonary Disease
J. P. Blonder, Boulder, CO

Abstract 22809
The Dual Neutral Endopeptidase/Endothelin Converting Enzyme Inhibitor SLV338 Inhibits Experimental Pulmonary Hypertension In Rats
D. M. Peters, Giessen, Germany

Abstract 22845
Effects of Home-Based Pulmonary Rehabilitation in COPD Patients—Adaptation to Patient’s Real Life
J. C. Marchioro, Sao Paulo, Brazil

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